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SOTALEX-80 Tablet

300.00৳

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Medicine Overview of Sotalex 80mg Tablet

Introduction

Sotalex 80 is used to treat various types of serious irregular heartbeat (arrhythmia) such as fibrillation and tachycardia. It is an anti-arrhythmic type of medicine and rapidly restores your heart to a steady and regular rhythm.

Sotalex 80 should be taken as advised by your doctor. It may be taken with or without food. Continuous monitoring of blood pressure and heart rate may be needed while taking this medicine. It is important that you keep taking it until your doctor decides it is safe to stop it. If you stop taking this medicine, you may get dangerous uneven heartbeats, which can be life-threatening.

The most common side effects of this medicine include nausea, vomiting, taste change, slow heart rate, and diarrhea. This medicine can also cause problems with your liver, lungs, nerves and thyroid gland. Ask your doctor what signs to look out for and report any symptoms you have. It takes a long time to clear from the body. You may continue to have side effects after you stop using it. Ask your doctor about ways to prevent or reduce them.

Before getting this medicine, you should let your doctor know if you have low blood pressure, drink a lot of alcohol or have liver, heart or thyroid problems. You should also inform your doctor about all other medicines that you are taking as many can seriously affect or be affected by this medicine. Some medicines like certain antibiotics and medicines for depression and mental illness should be avoided with this medicine.

Pregnant or breastfeeding women should consult their doctor before taking this medicine. Your doctor will carry out regular tests to check your liver and thyroid gland. You may also be advised other blood tests, x-rays, and eye tests both before and during treatment.

Uses of Sotalex 80

Arrhythmia

Side effects of Sotalex 80

Common

Dizziness
Fatigue
Slow heart rate
Breathlessness
Weakness

How to use Sotalex 80

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sotalex 80 may be taken with or without food, but it is better to take it at a fixed time.
Avoid Sotalex 80 with dairy products such as milk, cheese, curd, butter, paneer and ice cream.

How Sotalex 80 works

Sotalex 80 is an anti-arrhythmic medication. It regulates heart beat by blocking abnormal electrical signals in the heart.

What if you forget to take Sotalex 80?

If you miss a dose of Sotalex 80, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick Tips

Your doctor may get regular blood tests done to monitor sodium and potassium level, blood sugar level, kidney function, and lung function while you are taking this medicine.

Notify your doctor if you have any heart or kidney problem.

Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Please remind your doctor you are taking this medicine every time you visit him and ask him if the medicine can be stopped.

Brief Description

Indication

Supraventricular arrhythmias, Ventricular arrhythmias, Acute arrhythmias

Administration

Should be taken on an empty stomach. Take 1-2 hr before meals.

Adult Dose

Oral
Supraventricular and ventricular arrhythmias
Adult: Initially, 80 mg/day as single or in 2 divided doses, increased gradually every 2-3 days. Usual dose: 160-320 mg/day in 2 divided doses.Life-threatening ventricular arrhythmias
Adult: Initially, 80 mg bid, increased gradually every 3 days to 240-320 mg/day in divided doses if needed. Maintenance: 160-320 mg/day in divided doses. Max: 480-640 mg in divided doses.

Renal Dose

Renal impairment:
CrCl (ml/min)tDosage Recommendation
30-60tHalf the usual dose.
10-30tQuarter the usual dose.
<10tNot recommended.

Contraindication

Bronchial asthma or history of COPD, sick sinus syndrome, symptomatic sinus bradycardia, cardiogenic shock. 2nd and 3rd degree AV block, untreated phaeochromocytoma, torsades de pointes, congenital or acquired long QT syndromes, uncontrolled cardiac failure, cardiogenic shock, metabolic acidosis, hypotension, severe peripheral arterial disease, Raynaud’s disease, anaesthesia that causes myocardial depression. Renal impairment (CrCl <10 mL/min). Concomitant use w/ Ca channel blockers (e.g. verapamil and diltiazem).

Mode of Action

Sotalol is a non-cardioselective beta-blocker. It increases sinus cycle length, slows heart rate, decreases AV nodal conduction and increases AV nodal refractoriness. It also prolongs AV monophasic action potentials. However, it lacks intrinsic sympathomimetic and membrane-stabilising properties.

Precaution

Patients w/ well-compensated heart failure, myasthenia gravis, DM, 1st degree AV block. May mask symptoms of hyperthyroidism and hypoglycaemia. May worsen psoriasis. Patients undergoing major surgery requiring general anaesth. Avoid abrupt withdrawal as it may precipitate thyroid storm and exacerbate angina and MI. Renal impairment. Pregnancy and lactation. Monitoring Parameters Monitor BP, heart rate, serum creatinine; Mg and K levels.

Side Effect

>10%
Dyspnea (21%),Dizziness (20%),Fatigue (20%),Bradycardia (16%),Chest pain (16%),Palpitation (14%),Weakness (13%),Lightheadedness (12%)1-10%
Nausea/vomiting (10%),Edema (8%),Headache (8%),Sleep disturbances (8%),Abnormal ECG (7%),Diarrhea (7%),Extremity pain (7%),Hypotension (6%),Mental confusion (6%),Congestive heart failure (5%),Itching/rash (5%),Syncope (5%),Anxiety (4%),Depression (4%),Torsades de pointes or new ventricular tachycardia/fibrillation in patients with supraventricular arrhythmia (4%),Peripheral vascular disorders (3%),Impotence (2%),Proarrhythmic effect (1.5-2%),Torsades de pointes with history of sustained ventricular tachycardia (1%)Frequency Not Defined
Catechol hypersensitivity after abrupt withdrawal,Increased insulin requirement in diabetics

Potentially Fatal: Polymorphic ventricular tachycardia (very rare). Rebound hypertension.

Interaction

May increase risk of bradycardia w/ digoxin. May increase risk of arrhythmias w/ diuretics. May potentiate rebound HTN w/ clonidine. May prolong refractoriness w/ disopyramide, quinidine, procainamide, amiodarone and bepridil. May prolong QT interval w/ TCAs, phenothiazines, terfenadine and astemizole. Increased risk of torsades de pointes w/ K-depleting diuretics, erythromycin IV, halofantrine, pentamidine, and quinolones. May prolong neuromuscular blockade of tubocurarine. May reduce response to insulin and oral hypoglycaemics.

Potentially Fatal: Additive effect on AV conduction and ventricular function w/ verapamil and diltiazem.

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Categories: Cardiovascular System, Medicine

Size	Chest	Waist	Hips
XS	34	28	34
S	36	30	36
M	38	32	38
L	40	34	40
XL	42	36	42
2XL	44	38	44
All measurements are in INCHES and may vary a half inch in either direction.

Size	Chest	Waist	Hips
2XS	32	26	32
XS	34	28	34
S	36	30	36
M	38	32	38
L	40	34	40
XL	42	36	42
All measurements are in INCHES and may vary a half inch in either direction.

Size	Chest	Waist	Hips
XS	34	28	34
S	36	30	36
M	38	32	38
L	40	34	40
XL	42	36	42
2XL	44	38	44
All measurements are in INCHES and may vary a half inch in either direction.

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SOTALEX-80 Tablet

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SOTALEX-80 Tablet

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