APIXAN 2.5 mg Tablet
300.00৳
- Size Guide
Size Guide
DRESSEST-SHIRTBOTTOMSDRESSESSize Chest Waist Hips XS 34 28 34 S 36 30 36 M 38 32 38 L 40 34 40 XL 42 36 42 2XL 44 38 44 All measurements are in INCHES
and may vary a half inch in either direction.
T-SHIRTSize Chest Waist Hips 2XS 32 26 32 XS 34 28 34 S 36 30 36 M 38 32 38 L 40 34 40 XL 42 36 42 All measurements are in INCHES
and may vary a half inch in either direction.
BOTTOMSSize Chest Waist Hips XS 34 28 34 S 36 30 36 M 38 32 38 L 40 34 40 XL 42 36 42 2XL 44 38 44 All measurements are in INCHES
and may vary a half inch in either direction.
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Medicine Overview of Apixan 2.5 2.5mg Tablet
Apixan 2.5 is a medicine known as an anticoagulant or blood thinner. It helps prevent and treat blood clots. It is used to reduce the risk of stroke and heart attack. It prevents and treats clot formation in the veins of your legs, lungs, brain and heart.
Apixan 2.5 is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. It can be taken with or without food and it is best to take them at the same time each day. You may need to take this medicine for many years, even for life in some cases. Do not stop taking it or change the dose without guidance from your doctor. It could quickly put you more at risk of having a heart attack, stroke or thrombosis (formation of a blood clot within a blood vessel). You can reduce your risk of having a blood clot by making changes to your lifestyle, such as not smoking, eating a healthy diet, getting regular exercise and losing weight if you need to.
The most common side effect of Apixan 2.5 is bleeding more easily than normal, for example, having nosebleeds or bruising. If you experience any symptoms, tell your doctor immediately. Other side effects include low blood pressure, nausea, and skin rash.
Do not take this medicine if you have severe kidney or liver problems, if you are currently bleeding or if you are taking other medicines to reduce blood clotting. You should not breastfeed while using this medicine. Unlike other anticoagulants, a regular blood test (PT-INR) is not required while taking this medicine.
- Deep vein thrombosis
- Pulmonary embolism
- Stroke prevention
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For best results, take Apixan 2.5 at the same time every day. It is better to take at night with meals
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It interacts less with food or other medicines. Hence, frequent dose changes are not required.
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It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
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Inform your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
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If you are going to have a surgery or dental treatment, you may be asked to stop taking Apixan 2.5 temporarily.
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Notify your doctor if you have any kidney problem.
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Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
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Do not stop taking medication without talking to your doctor.
Adult
Prevention of VTE: Elective hip or knee replacement surgery
Tablet 2.5 mg twice daily. Initial dose should be taken 12-24 hr post-op.
Recommended duration of treatment: Patient undergoing hip replacement surgery 32-38 days.
Patient undergoing knee replacement surgery 10-14 days.Prevention of stroke and systemic embolism in non-valvular atrial fibrillation
Adult: 5 mg bid.
Decrease dose to 2.5 mg PO BID in patients with any 2 of the following characteristics:
Age ?80 years
Weight ?60 kg
Serum creatinine ?1.5 mg/dL
Oral
Deep vein thrombosis, Pulmonary embolism
Adult: 10 mg bid for 7 days, followed by 5 mg bid.
Prevention of recurrence: 2.5 mg bid after at least 6 mth of treatment.
Hepatic impairment
Mild: No dosage adjustment required
Moderate: Patients may have intrinsic coagulation abnormalities; data are limited and no recommendations are available
Severe: Not recommended
Deep Vein Thrombosis: No dose adjustment recommended; clinical efficacy and safety studies did not enroll patients with ESRD on dialysis or patients with a CrCl <15 mL/min; dosing recommendations are based on pharmacokinetic and pharmacodynamic (anti-FXa activity) data in study subjects with ESRD maintained on dialysisRenal impairment (nonvalvular atrial fibrillation)
Mild-to-moderate: No dosage adjustment required
Serum creatinine ?1.5 mg/dL: Decrease dose to 2.5 mg BID if patient has 1 additional characteristic of age ?80 years or weight ?60 kg
ESRD maintained on hemodialysis: 5 mg BID; decrease dose to 2.5 mg BID if 1 additional characteristic of age ?80 years or weight ?60 kg is present
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Potentially Fatal: Epidural or spinal haematoma, fatal bleeding.
There are no adequate and well-controlled studies in pregnant womenTreatment is likely to increase the risk of hemorrhage during pregnancy and delivery
Use of anticoagulants, during pregnancy, may increase risk of bleeding in fetus and neonate
Pregnancy confers an increased risk of thromboembolism that is higher for women with underlying thromboembolic disease and certain high-risk pregnancy conditions
Published data describe that women with a previous history of venous thrombosis are at high risk for recurrence during pregnancy
Therapy should be administered during pregnancy only if the potential benefit outweighs the potential risk to the mother and fetus
Animal studies
Treatment of pregnant rats, rabbits, and mice after implantation until the end of gestation resulted in fetal exposure to apixaban, but was not associated with increased risk for fetal malformations or toxicity
Labor and delivery
All patients receiving anticoagulants, including pregnant women, are at risk for bleeding; use during labor or delivery in women who are receiving neuraxial anesthesia may result in epidural or spinal hematomas; consider use of a shorter acting anticoagulant as delivery approaches
Consider the risks of bleeding and of stroke in this setting
Lactation
There are no data on presence of drug metabolites in human milk, effects on breastfed child, or the effects on milk production; the drug and/or its metabolites were present in milk of rats
Rats excrete apixaban in milk (12% of the maternal dose)
Because human exposure through milk is unknown, instruct women to either discontinue breastfeeding or to discontinue apixaban therapy, taking into account the importance of the drug to the mother
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