Nafgal Cream 2% (30 gm)
Original price was: 230.00৳ .218.50৳ Current price is: 218.50৳ .
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Indications
Nafgal cream is an allylamine antifungal indicated for the treatment of interdigital tinea pedis, tinea cruris, and tinea corporis caused by the organism Trichophyton Rubrum.
* রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন‘
Description
Nafgal is a synthetic, broad spectrum, antifungal agent and allylamine derivative. The following in vitro data are available, but their clinical significance is unknown. Nafgal has been shown to exhibit fungicidal activity in vitro against a broad spectrum of organisms including Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Epidermophyton floccosum, and Microsporum canis, Microsporum audouini, and Microsporum gypseum; and fungistatic activity against Candida species including Candida albicans. However it is only used to treat the organisms listed in the indications.
Pharmacology
The exact mechanism of action against fungi is not known, Naftifine Hydrochloride appears to interfere with sterol biosynthesis by inhibiting the enzyme squalene 2, 3-epoxidase. This inhibition of enzyme activity results in decreased amounts of sterols, especially ergosterol and a corresponding accumulation of squalene in the cells.
Dosage & Administration
Apply a thin layer of Naftifine Hydrochloride Cream once-daily to the affected areas plus half inch margin of healthy surrounding skin for 2 weeks or as directed by the physician.
Use in Children and Adolescents: The safety and effectiveness of Naftifine Hydrochloride have been established
in the age group of 12-17 years with interdigital tinea pedis and tinea cruris.
* রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন‘
Interaction
No information is available.
Side Effects
The most common adverse reaction (≥1%) is pruritus.
Pregnancy & Lactation
Pregnancy Category B. There are no adequate and well-controlled studies of Naftifine Cream in pregnant women. Because animal reproduction studies are not always predictive of human response, Naftifine Cream should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Naftifine Cream is administered to a nursing woman.
Precautions & Warnings
If irritation or sensitivity develops with the use of Nafgal Cream, treatment should be discontinued.
Overdose Effects
An overdose of Nafgal topical is not expected to be dangerous.
Therapeutic Class
Topical Antifungal preparations
Storage Conditions
Store below 30°C, away from light and in a dry place. Keep out of the reach of children.
Also available as:
10 gm tube: ৳ 80.00
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