Ritch Oral Suspension 30 mg/5 ml (50 ml bottle)
Original price was: 55.00৳ .52.25৳ Current price is: 52.25৳ .
Indications
Allergic rhinitis: Ritch is indicated for the relief of symptoms associated with seasonal and perennial allergic rhinitis, in adults and children 12 years of age and over. Symptoms treated effectively include sneezing, rhinorrhea, lacrimation, itchy, red eyes and itchy nose/palate/throat. Ritch improves health-related quality of life and work/activity productivity.
Chronic idiopathic urticaria: Ritch is indicated for the relief of symptoms associated with chronic idiopathic urticaria in adults and children 12 years of age and older. Ritch significantly reduces the signs and symptoms of chronic idiopathic urticaria, the number of wheals, and pruritus. Ritch improves health-related quality of life and work/activity productivity.
Pharmacology
The H1 histamine receptor is responsible for mediating hypersensitivity and allergic reactions. Exposure to allergen results in the degranulation of mast cells and basophils, which then release histamine and other inflammatory mediators. Histamine binds to, and activates, H1 receptors, which results in the further release of pro-inflammatory cytokines, such as interleukins, from basophils and mast cells. These downstream effects of histamine binding are responsible for a wide variety of allergic symptoms, such as pruritus, rhinorrhea, and watery eyes.
Fexofenadine is considered an “inverse agonist” of the H1 receptor because it binds to and stabilizes the inactive form of the receptor, preventing its activation and subsequent downstream effects. It has a potent and selective affinity for H1 receptors, and there is no evidence that it carries antidopaminergic, antiserotonergic, anticholinergic, sedative, or adrenergic blocking activity. Fexofenadine does not cross the blood-brain barrier and thus is unlikely to cause significant CNS effects.
Dosage & Administration
Allergic Rhinitis-
Adults and children 12 years and older:
- Tablet: 60 mg twice daily or 120 mg once daily or 180 mg once daily
- In case of impaired renal function: 60 mg once daily
Children from 6 to 11 years:
- Tablet: 30 mg twice daily or 60 mg once daily
- In case of impaired renal function: 30 mg once daily
Children from 2 to 11 years
- Suspension: 30 mg or 5 ml twice daily
- In case of impaired renal function: 30 mg or 5 ml once daily
Chronic Idiopathic Urticaria-
Adults and children 12 years and older:
- Tablet: 60 mg twice daily or 120 mg once daily or 180 mg once daily
- In case of impaired renal function: 60 mg once daily
Children from 6 to 11 years:
- Tablet: 30 mg twice daily or 60 mg once daily
- In case of impaired renal function: 30 mg once daily
Children from 6 months to less than 2 years:
- Suspension: 15 mg or 2.5 ml (1/2 tsp) twice daily
- In case of impaired renal function: 15 mg or 2.5 ml (1/2 tsp) once daily
Children from 2 to 11 years:
- Suspension: 30 mg or 5 ml (1 tsp) twice daily
- In case of impaired renal function: 30 mg or 5 ml (1 tsp) once daily
Interaction
Contraindications
Side Effects
Pregnancy & Lactation
There are no adequate data from the use of Fexofenadine hydrochloride in pregnant women. Limited animal studies do not indicate direct or indirect harmful effects with respect to effects on pregnancy, embryonal/foetal development, parturition or postnatal development. Fexofenadine hydrochloride should not be used during pregnancy unless clearly necessary.
There are no data on the content of human milk after administering Fexofenadine hydrochloride. However, when Terfenadine was administered to nursing mothers Fexofenadine was found to cross into human breast milk. Therefore, Fexofenadine hydrochloride is not recommended for mothers breast-feeding their babies. No human data on the effect of Fexofenadine hydrochloride on fertility are available. In mice, there was no effect on fertility with Fexofenadine hydrochloride treatment.
Precautions & Warnings
As with most new medicinal products there is only limited data in the older people and renally or hepatically impaired patients. Ritch should be administered with care in these special groups. Patients with a history of or ongoing cardiovascular disease should be warned that, antihistamines as a medicine class, have been associated with the adverse reactions, tachycardia and palpitations.
Effects on ability to drive and use machines: On the basis of the pharmacodynamic profile and reported adverse reactions it is unlikely that Ritch tablets will produce an effect on the ability to drive or use machines. In objective tests, Ritch has been shown to have no significant effects on central nervous system function. This means that patients may drive or perform tasks that require concentration. However, in order to identify sensitive people who have an unusual reaction to medicinal products, it is advisable to check the individual response before driving or performing complicated tasks.
Use in Special Populations
Renal and hepatic impaired patient: The pharmacokinetics of fexofenadine are altered in individuals with renal impairment. Based on increases in bioavailability and half-life, a dose of 60 mg once daily is recommended as the starting dose in patients with decreased renal function. Moderate to severe hepatic disease does not affect the pharmacokinetics of fexofenadine substantially.
Elderly patient: Adverse events were similar in this group compared to patients under 65 years of age. Nevertheless, the pharmacokinetics of fexofenadine is altered (increased bioavailability) in individuals over 65 years of age.
Overdose Effects
Therapeutic Class
Storage Conditions
Chemical Structure
| Molecular Formula : | C32H39NO4 |
| Chemical Structure : |  |
Common Questions about Ritch 30 mg/5 ml Suspension
What is Ritch 30 mg/5 ml Suspension?
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Can Ritch 30 mg/5 ml Suspension make you sleepy?
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How quickly does Ritch 30 mg/5 ml Suspension work?
Does Ritch 30 mg/5 ml Suspension relieve symptoms of outdoor and indoor allergies?
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Can I take antacids while taking Ritch 30 mg/5 ml Suspension?
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Is there any food or drink that I need to avoid while taking Ritch 30 mg/5 ml Suspension?
Can Ritch 30 mg/5 ml Suspension cause heart problems?
Quick Tips
- Ritch 30 mg/5 ml Suspension is an antihistaminic medication. It treats allergy symptoms such as itching, swelling, and rashes by blocking the effects of a chemical messenger (histamine) in the body.
- Ritch 30 mg/5 ml Suspension is less likely to make you feel sleepy than some other similar medicines.
- Do not take Ritch 30 mg/5 ml Suspension with any fruit juices (such as apple, orange, or grapefruit) as they might make the drug less effective.
- Ritch 30 mg/5 ml Suspension may cause nausea. Stick to simple meals, and do not eat rich or spicy food.
- Avoid using antacids 30 minutes before or after taking Ritch 30 mg/5 ml Suspension. It can make it harder for your body to absorb this medication.
