MEROZOLYN 5 Tablet

250.00৳ 

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Medicine Overview of Merozolyn 5mg Tablet

Introduction

Merozolyn is a type of diuretic (water pill) medicine. This medicine reduces excess fluid levels in the body and is used to treat edema (fluid overload) associated with heart, liver, kidney, or lung disease. It is also used in treatment of hypertension (high blood pressure).

Merozolyn makes you lose excess water through urine. It may be used alone or in combination with other medicines. This medicine should be taken only during day time to avoid frequent urination at night. You must take this medicine in the dose and duration as advised by the doctor and never stop it abruptly without consulting the doctor.

Common side effects of this medicine include headache, nausea, and dizziness. Consult your doctor if these side effects bother you. Before taking this medicine, it is better to let your doctor know if you are suffering from any kidney or liver disease. Also, pregnant women and breastfeeding mothers should consult a doctor before taking it. You must inform the doctor about all the other medicines that you are taking apart from this medicine. Regular monitoring of kidney function and electrolytes is important while using this medicine.

 

Uses of Merozolyn
  • Hypertension (high blood pressure)
Side effects of Merozolyn
Common
  • Headache
  • Nausea
  • Increased blood uric acid
  • Decreased potassium level in blood
  • Glucose intolerance
  • Altered blood lipid level
How to use Merozolyn
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Merozolyn is to be taken with food.
How Merozolyn works
Merozolyn is a thiazide diuretic. It lowers blood pressure and fluid retention in edema by removing the extra water and certain electrolytes from the body. Over time it also works by relaxing blood vessels and improving blood flow.
What if you forget to take Merozolyn?
If you miss a dose of Merozolyn, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
  • Take it in the morning with breakfast to avoid getting up at night to urinate.
  • It makes you feel dizzy. Avoid driving and attention requiring activity until you know how it affects you.
  • Avoid alcohol intake while taking Merozolyn as it may increase the dizziness.
  • It may cause a sudden drop of sodium level in blood. Avoid low sodium diet while you are taking this medication.
  • Monitor your blood pressure after starting Merozolyn, and notify your doctor if it does not lower down.
  • Notify your doctor if you experience dizziness, tiredness, or muscle weakness that does not go away.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Brief Description
Indication
Oedema, Hypertension
Administration
Should be taken with food. Take after breakfast.
Adult Dose
Oral
Hypertension
Adult: Initially, 1.25 mg daily, adjusted after 3-4 wk according to response. Usual dose: 2.5-5 mg daily, either alone or with other antihypertensives.
Maintenance dose: 5 mg on alternate days.
Formulations with enhanced bioavailability: 0.5-1 mg daily.Oedema
Adult: 5-10 mg daily, increased if necessary to 20 mg daily. Max: 80 mg in 24 hr.

Elderly: Initially, 2.5 mg/day or every other day.

 

Child Dose
Oedema
0.2-0.4 mg/kg/day PO in single daily dose or divided q12hr
Renal Dose
Renal impairment: Not necessary to supplement dose in hemodialysis or peritoneal dialysis
Contraindication
Anuria; hepatic coma or pre-coma. Pregnancy.
Mode of Action
Metolazone is a thiazide-like diuretic. It inhibits reabsorption of sodium in the distal tubules resulting in increased excretion of sodium and water, as well as potassium and hydrogen ions.

 

Precaution

Pre-diabetes or DM; gout; SLE; hepatic and renal impairment; hypercholesterolaemia. Correct electrolyte disturbances prior to therapy. Risk of cross-sensitivity with sulfonamides, sulfonylureas, carbonic anhydrase inhibitors, thiazides and loop diuretics.

Lactation: Not recommended

 

Side Effect

Chest pain, palpitation, necrotising angiitis, orthostatic hypotension, syncope, venous thrombosis, vertigo, volume depletion; depression, dizziness, chills, drowsiness, fatigue, restlessness, headache, lightheadedness; petechiae, photosensitivity, hypersensitivity reactions; gout attacks, electrolyte disturbances; abdominal bloating, diarrhoea, abdominal pain, anorexia, constipation, epigastric distress, nausea, xerostomia, pancreatitis, vomiting; impotence; aplastic anaemia, thrombocytopenia, haemoconcentration, leukopenia; cholestatic jaundice, hepatitis; joint pain, muscle cramps, weakness, neuropathy, paraesthesia; blurred vision; increased BUN, glucosuria.

Potentially Fatal: Stevens-Johnson syndrome, toxic epidermal necrolysis.

 

Interaction

Hypotensive and nephrotoxic effects of ACE inhibitors may be enhanced. Absorption may be reduced with bile acid sequestrants. Hyperglycaemic effect may be enhanced with diazoxide. May increase serum concentration and QTc-prolonging effect of dofetilide. May reduce lithium excretion. Hypotensive effect may be increased with alcohol.

Potentially Fatal: Increased risk of nephrotoxicity with ciclosporin. Severe electrolyte disturbances may occur with furosemide.

 

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MEROZOLYN 5 Tablet

250.00৳ 

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    250.00৳ 

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