In an interview with CNBC, Andrew Dudum, CEO of Hims & Hers, stated that the company has partnered with one of the largest manufacturers of generics in the U.S. in order to ensure that they would not fall prey to supply issues. Their compounded version of the GLP-1 drug semaglutide will be prescribed by a physician through their own telehealth platform. Eating plenty of protein, fiber, and water-rich foods, as well as exercising regularly, are all healthy, natural ways to help regulate your appetite. Therefore, Kelvas says, while controlling hunger through appetite suppression can help, it’s also crucial for you to address and manage these other factors. Some reasons include stress, boredom, emotional comfort, and social gatherings.

  • These infections are often polymicrobial and Staphylococcus aureus and Streptococcus pyogenes are among the most common organisms [7].
  • A FeaturePaper should be a substantial original Article that involves several techniques or approaches, provides an outlook forfuture research directions and describes possible research applications.
  • Needles are radio-opaque and may be readily identified on plain radiographs (Fig. 7) or CT (Fig. 8), further highlighting the value of obtaining X-rays in PWID who present with soft tissue infections.
  • Most local health departments offer free tetanus boosters, which will protect you from tetanus for five years, so you should r get one.
  • Sadly, something called the “drug ceiling effect” can occur, where the drug will reach its maximum effect regardless of taking higher doses.
  • You could see the huge vegetation growth just floating on the heart valve, and when this occurs, it can be extremely dangerous.

Bone and joint complications

  • Where there is difficulty in assessing the pseudoaneurysm and its neck with ultrasound, CT or MR angiography can be performed for further evaluation (Figs. 18 and 19).
  • In PWID, abscesses may develop in deep locations due to direct extension from the site of injection, such as from the groin into the pelvis or retroperitoneum, or as a result of haematogenous seeding of distant locations.
  • There could be a greater risk for unknown side effects or interactions, said Takyrbashev.

Find support for a specific problem in the support section of our website. The aim is to provide a snapshot of some of themost exciting work published in the various research areas of the journal. Consumers need to be aware that they cannot ask the FDA to intervene if they experience quality problems or adverse reactions.

  • CT is also important in the evaluation of sites such as the sacroiliac or sternoclavicular joints where plain film assessment is limited [24].
  • People injecting drugs have a high prevalence of psychotic illness, personality disorders, and common mental health problems such as anxiety and depression.
  • For example, the administration of an IV opioid (narcotic) medication could result in respiratory depression.
  • When this happens, a person will likely experience serious tissue damage, including ulceration and tissue death, if they do not receive treatment in time.
  • Radiographs cannot reliably detect effusions in many joints, however, including the hips and shoulders.

Guidelines Related to Intravenous Therapy

Feel free to ask questions so you can be well-informed and be involved in making decisions about your treatment. In a 2015 study, adverse side effects were more common in people who received opioids by IV compared to other methods. People most commonly inject into their forearm, however, users may also choose locations on their legs, neck, hands, feet, and groin.

IV Drug Use and Potential Complications

Hims & Hers Selling GLP-1 Weight Loss Drugs Like Wegovy for 85% Less: What to Know

Cellulitis is a common bacterial skin infection that can result in red streaking of the skin, tenderness, inflammation and pain in the infected area. If cellulitis is left untreated, it can cause serious complications and health problems. HIV is a chronic autoimmune disease that can occur from a contaminated needle. IV drug users, especially those who share needles, are at an increased risk of developing HIV.

Are compounded drugs safe to use?

Treatment can ease your symptoms and might help prevent heart problems and other complications. You can take prescription opioids orally or receive them intravenously (IV). Risk may be greater with IV IV Drug Use and Potential Complications use since it puts the opioid right into your bloodstream, heightening its effects. In fact, we recommend that you not touch the items inside of the kit for any reason unless you absolutely have to.

Vascular complications are common in PWID, can occur locally at the injection site or at a distant location and may be arterial or venous in nature. They occur more frequently when injected drug users progress from injection of superficial upper limb veins to larger and deeper vessels such as the femoral vein in the groin or jugular vein in the neck [15, 26]. Vascular complications may manifest as injury to the vessel wall, interruption of blood flow in the lumen with resultant ischaemia or haematogenous spread of a pathogen from the injection site. MRI will show a joint effusion with synovial thickening and enhancement, indicative of active synovitis (Fig. ​(Fig.15)15) [24].

Story – University of Maryland, Baltimore


Posted: Mon, 18 Dec 2023 08:00:00 GMT [source]


  • Our resources can help you learn about the health impacts of drug use, how to reduce harm and the services and supports available in NYC.
  • The extravasation grade diagnosis will determine the treatment that the person receives.
  • Many institutions will hang smaller volume normal saline continuous infusion bags just to serve as an additional reminder that these patients should not receive large amounts of primary fluids.
  • In cellulitis, high T2 and STIR signal intensity with corresponding T1 signal intensity of the subcutaneous tissues with overlying skin thickening is seen, and there is enhancement following gadolinium administration [8].

Abscesses And Systemic Infections

IV Drug Use and Potential Complications

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